Vitamin A Palmitate (RETINYL PALMITATE)
Global Regulation Summary
Overview of current status across major international markets.
Detailed Regional Status
| Region | Status | Max Conc. | Conditions | Source |
|---|---|---|---|---|
| πͺπΊ EU | Unknown | - | - | Official β |
| πΊπΈ USA | Unknown | - | - | Official β |
| π―π΅ Japan | Unknown | - | - | Official β |
| π°π· Korea | Unknown | - | - | Official β |
| π¬π§ UK | Unknown | - | - | Official β |
πΏ Natural Sources
Most abundant form of vitamin A storage in animals. Found naturally in animal liver (particularly fish liver such as cod, halibut, and salmon), egg yolks, and dairy products. The liver stores retinyl palmitate in hepatic stellate cells.
π How It's Made
Synthesized through esterification of retinol (vitamin A) with palmitic acid. Modern methods use enzymatic approaches: hydrolysis of retinyl acetate to retinol by potassium hydroxide, followed by esterification catalyzed by immobilized lipase in non-aqueous systems. Fed-batch fermentation can produce 69.96 mg/L using microbial production.
π Uses in Cosmetics
Used at 0.1-0.5% in moisturizers, serums, and anti-aging creams; 0.05-0.2% in haircare products. Functions as a precursor to retinoic acid, promoting skin cell turnover and collagen production. More stable than retinol, making it suitable for light-sensitive formulations.
π¬ Other Applications
Common vitamin supplement for treating vitamin A deficiency, available in oral and injectable forms under brand names Aquasol A and Palmitate A. Used in animal nutrition and feed supplements.
π‘ Fun Facts
- β’ First safety assessment by the Cosmetic Ingredient Review Panel in 1987 confirmed it safe for cosmetic use, reaffirmed in 2005
- β’ The palmitate ester form is how all fish and animals naturally store vitamin A in their liver fat cells
- β’ Fish liver oil has been universally recognized as the best natural source of vitamin A since early nutritional research
Frequently Asked Questions
What is RETINYL PALMITATE used for in cosmetics?
RETINYL PALMITATE is primarily used for skin conditioning in cosmetic products. It also serves as antioxidant. The ingredient is commonly found in moisturizers, lotions, and creams.
Which countries regulate RETINYL PALMITATE?
RETINYL PALMITATE is approved for cosmetic use in all major markets: , with no significant restrictions.
Where can I find official regulation information about RETINYL PALMITATE?
Official information about RETINYL PALMITATE regulations can be found on government websites: EU CosIng database, US FDA Cosmetics page, Japan MHLW cosmetics standards, UK Government cosmetics guidance, and Korea MFDS. Always verify regulatory status with these official sources before making formulation decisions.
Disclaimer
The information on this website is for educational and informational purposes only and is not intended as medical advice. While we strive for accuracy based on official government databases, cosmetic regulations change frequently. Always consult with a qualified professional or refer to the latest official regulatory documents for compliance. We are not responsible for any actions taken based on the information provided here.